Why do blood clots form during coronavirus infection?
Blood clots are the most common cause of sudden death and disability in COVID 19.
The new coronavirus affects mainly 2 types of cells – epithelial (respiratory tract) and endothelial (vascular walls). With coronavirus infection, microangiopathy develops, in which the walls of small blood vessels are damaged. Because of this, microthrombi can form, then blood clots and the blood supply to internal organs is impeded.
The inflammatory response in severe coronavirus infection is very powerful, it is also called a cytokine storm. The complement system, which is responsible for recognizing viruses and cleansing the blood of dead cells, is overly activated. As a result, the level of platelets in the blood rises sharply and the risk of blood clots increases.
Also, blood clots can form against a background of high fever and insufficient fluid intake, when the blood becomes thicker;
Who is more at risk for blood clots from coronavirus infection?
The risk of blood clots in coronavirus is increased in people with diabetes mellitus with a genetic predisposition to thrombosis. There is a high risk of blockage of blood vessels by clots in patients who are overweight and in patients with a sedentary lifestyle.
Why are anticoagulants prescribed for covid-19?
Anticoagulants can double the survival rate of coronavirus patients, according to a study published in the Journal of the American College of Cardiology. Specialists at the Mount Sinai Medical Complex in New York noted that anticoagulants play an important role in the treatment of patients with COVID-19, and they can prevent possible deaths associated with coronavirus, including heart attack, stroke and pulmonary embolism.
When should you take anticoagulants?
Anticoagulants are used for coronavirus infection with lung tissue damage in the complex therapy of inpatients and outpatients. It should be taken during the acute phase of the disease, and after recovery within 45 days.
How does Rivaksan work?
In coronavirus infection, factor Xa provokes the formation of a thrombus from fibrin filaments and, under the influence of thrombin, activates platelets. One molecule of factor Xa is capable of forming more than a thousand molecules of thrombin, in addition, the reaction rate of the coagulation cascade increases 300,000 times, leading to a “thrombin explosion”. Rivaxan (rivaxan) inhibits the increase in thrombin formation, thereby preventing clot formation and attachment to the vessel wall.
Rivaxan is rapidly absorbed, reaching its maximum concentration in the blood within 2-4 hours after taking the pill.
How can you protect yourself from getting infected with covid-19?
There are no specific methods for preventing covid-19. Therefore, the only effective way to protect yourself from this infection is to avoid contact with sick people as much as possible, and if this is impossible, keep a great distance, wear a mask (for example, in a store, pharmacy), use an antiseptic.
